Addison’s disease, also known as adrenal insufficiency, is a rare condition in which the body doesn’t produce certain hormones. Addison’s disease is rare; only 1 in 100,000 people have it.
Adrenal glands are located above the kidneys and produce hormones the body requires. In Addison’s disease, the adrenal cortex is damagedand doesn’t produce enough aldosterone and cortisol hormones.
Cortisol is released during stress, and it helps regulate the body’s carbohydrates, fats, and proteins. It also controls blood pressure, cardiovascularfunction, and inflammation. At the same time, aldosterone has a key role in balancing body fluids and salts. Low levels of aldosterone cause a drop in blood pressure.
The most common cause of Addison’s disease, according to research, is the autoimmune response from the body in which the body’s immune system attacks body tissues, especially the adrenal cortex, the outer portion of the adrenal gland. Other causes include: